Methanol → 2-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-1,2,3,4-tetrahydroisoquinoline

HRID 169684Notes

Reaction equation

HRID 169684 reaction equation
[Br:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:14][CH3:15])[cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][cH:10]1.[CH2:16]1[NH:17][CH2:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]21.[CH3:26][OH:27].[Cl:28][CH2:29][Cl:30]>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([O:14][CH3:15])[cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][cH:10]1)[N:17]1[CH2:16][c:25]2[c:20]([cH:21][cH:22][cH:23][cH:24]2)[CH2:19][CH2:18]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 70461,2,3,4-TetrahydroisoquinolineHCID 129372541-(2-Bromoethoxy)2-methoxy-4-nitrobenzene

Product 1

HCID 688163292-[2-(2-Methoxy-4-nitrophenoxy)ethyl]-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-fc8b401dac954053a700a89717879df3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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