2beta-Carbomethoxy-3beta-(4-trimethylsilylphenyl)tropane → Win 35428

HRID 1698756

Reaction equation

HRID 1698756 reaction equation
[C:1]([C@H:5]1[C@@H:11]([C:12]2[CH:17]=[CH:16][C:15]([Si](C)(C)C)=[CH:14][CH:13]=2)[CH2:10][C@H:9]2[N:22]([CH3:23])[C@@H:6]1[CH2:7][CH2:8]2)([O:3][CH3:4])=[O:2].[F:24]C1C=CC([Mg]Br)=CC=1>>[C:1]([C@H:5]1[C@@H:11]([C:12]2[CH:17]=[CH:16][C:15]([F:24])=[CH:14][CH:13]=2)[CH2:10][C@H:9]2[N:22]([CH3:23])[C@@H:6]1[CH2:7][CH2:8]2)([O:3][CH3:4])=[O:2]

Participants

3

Reactant 2

HCID 697363762beta-Carbomethoxy-3beta-(4-trimethylsilylphenyl)tropaneHCID 178418676HCID 178418676, compound

Product 1

HCID 105056Win 35428

Procedure

This compound was synthesized using a similar reaction as 2β-Carbomethoxy-3β-(4′-trimethylsilylphenyl)tropane starting with anhydroecognine methyl ester and 4-fluorophenylmagnesium bromide.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-f18241a497244ccbb8c89681938006fd
Source dataset
uspto-grants-2002_02
Patent number
US06344179B1

Linked notes

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