HCID 18319637, compound → HCID 18319549, compound
Reaction equation
[OH:1][CH2:2][C:3]1[C:13]2[O:12][CH2:11][CH2:10][C:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:8][C:7]=2[CH:6]=[CH:5][CH:4]=1>[O-2].[Mn+4].[O-2]>[CH:2]([C:3]1[C:13]2[O:12][CH2:11][CH2:10][C:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:8][C:7]=2[CH:6]=[CH:5][CH:4]=1)=[O:1]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of ethyl 2,3-dihydro-9-hydroxymethyl-1-benzoxepin-4-carboxylate (0.45 g) and manganese (IV) oxide (4.5 g) was stirred under reflux for 1 hour and filtered off. The filtrate was evaporated in vacuo to give a solid of ethyl 2,3-dihydro-9-formyl-1-benzoxepin-4-carboxylate (0.43 g).
Workup
- temperatureunder reflux for 1 hour
- filtrationfiltered off
- customThe filtrate was evaporated in vacuo
Sources & evidence
- ORD record
- ord-6af95d4826784047ac077d193790cff0
- Source dataset
- uspto-grants-2002_02
- Patent number
- US06346527B1
Reaction notes
Loading…