Methanol → Tert-butyl 4-(5-amino-3-chloropyridin-2-yl)piperazine-1-carboxylate
Reaction equation
[BH4-:24].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([N+:21]([O-:22])=[O:23])[cH:18][c:19]2[Cl:20])[CH2:12][CH2:13]1.[CH3:26][OH:27].[Na+:25].[Ni:34]([Cl:35])[Cl:36].[OH2:28].[OH2:29].[OH2:30].[OH2:31].[OH2:32].[OH2:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][c:17]([NH2:21])[cH:18][c:19]2[Cl:20])[CH2:12][CH2:13]1Participants
7
Sources & evidence
- ORD record
- ord-9d4bcbfb70e0400fb86ef7cceed5d860
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…