HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one → 2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369367 | — |
| Reactant | p-Chlorocinnamyl chloride | HCID 53728250 | — |
| Product | 2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 54242121 | 72.5% |
Reaction Steps
Using 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one and 4-chlorocinnamyl chloride as starting materials, the procedures of Example 12 were repeated likewise, whereby the title compound was obtained in a yield of 72.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06348468B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-10f0fb7a10bf48da89d6b70ffb656aca |
| Source note | uspto-grants-2002_02 |