HCID 12923316, compound → 2-Methyl-3-tert.-butoxypropan-1-ol

Reaction equation

[C:1]([O:5][CH2:6][CH:7]([CH3:15])[C:8](OC(C)(C)C)=[O:9])([CH3:4])([CH3:3])[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[C:1]([O:5][CH2:6][CH:7]([CH3:15])[CH2:8][OH:9])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 12923316HCID 12923316, compound

HCID 21226445Aluminium lithium hydride

Product 1

HCID 125367792-Methyl-3-tert.-butoxypropan-1-olYield 88%

Procedure

Reduction of rac.-tert. butyl 3-tert.butoxy-2-methylpropionate was carried out with lithium aluminum hydride using the procedure described in Example 2. The resulting rac.-3-tert. butoxy-2-methyl-1-propanol was obtained in 88% yield as a colorless liquid, b.p. 70°-72° C. (10 mm Hg.).

Sources & evidence

ORD record: ord-8ede9dc7dd02442c8cc61b630dfe8d69
Source dataset: uspto-grants-1980_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04191842

Reaction notes

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