Methylamine hydrochloride → N-methyl-5-chloro-2-indanamine

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH2:7][C:6](=O)[CH2:5]2.Cl.[CH3:13][NH2:14]>>[CH3:13][NH:14][CH:6]1[CH2:5][C:4]2[C:8](=[CH:9][CH:10]=[C:2]([Cl:1])[CH:3]=2)[CH2:7]1

Participants

Reactant 2

HCID 6364545Methylamine hydrochloride

HCID 218375355-Chloro-1H-inden-2(3H)-one

Product 1

HCID 20347845N-methyl-5-chloro-2-indanamine

Procedure

Following the procedure of Example 5, 5-chloro-2-indanone and methylamine hydrochloride gave N-methyl-5-chloro-2-indanamine.

Sources & evidence

ORD record: ord-6760de480a694df4aa5755c278572747
Source dataset: uspto-grants-1980_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04192888

Reaction notes

Loading…