Ammonia → HCID 178456954, compound
Reaction equation
[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][S:11][CH:12]([CH3:15])[CH2:13][NH2:14])[N:9]=1)[C:2]([NH2:4])=[NH:3].COC1C(OC)=NS(=O)N=1.N(C1SC=C(CSC(C)C[NH:39][C:40]2[C:44](OC)=[N:43][S:42](=[O:47])[N:41]=2)N=1)C(N)=N.N>>[NH:1]([C:5]1[S:6][CH:7]=[C:8]([CH2:10][S:11][CH:12]([CH3:15])[CH2:13][NH:14][C:44]2[C:40]([NH2:39])=[N:41][S:42](=[O:47])[N:43]=2)[N:9]=1)[C:2]([NH2:4])=[NH:3]Participants
5
Procedure
When a methanolic solution of 2-[(guanidinothiazol-4-yl)methylthio]propylamine is reacted with 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide [prepared in Example 4, Step A], and the resultant 3-{2-[(2-guanidinothiazol-4-yl)methylthio]propylamino}-4-methoxy-1,2,5-thiadiazole 1-oxide is treated with excess ammonia by the procedure in Example 35, the title compound is thereby produced.