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Sodium Hydroxide → HCID 12961719, compound

HRID 1702904
Notes
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Reaction equation

HRID 1702904 reaction equation
C[O:2][C:3](=[O:30])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[N:13]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)[C:12]1=[O:29].[OH-].[Na+]>CO>[CH3:28][C:25]1[CH:24]=[CH:23][C:22]([N:13]2[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:15][N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:30])=[O:2])[C:12]2=[O:29])=[CH:27][CH:26]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53800202HCID 53800202, compound

Product 1

HCID 12961719HCID 12961719, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product is produced as described in example 18 from 18.1 g of 8-[3-(4-methylphenyl)-2-oxo-4-phenyl-4-imidazolin-1-yl] caprylic acid methyl ester and 1.8 g of NaOH in 90 cc. of methanol. Further purification by chromatography on silicic acid gel using chloroform as eluant.

Workup

  1. custom
The product is produced
  • customFurther purification by chromatography on silicic acid gel
  • Sources & evidence

    ORD record
    ord-a00c09ff21264fee87c4b89be542a637
    Source dataset
    uspto-grants-1982_09
    DOI
    10.6084/m9.figshare.5104873.v1
    Patent number
    US04349684

    Reaction notes

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    On this pageParticipantsProcedureWorkupSources & evidenceReaction notes