Phenol → Tert-butyl 4-{[2,6-dichloro-4-(phenylmethoxy)phenoxy]methyl}piperidinecarboxylate

HRID 170331

Reaction equation

HRID 170331 reaction equation
[Cl:23][c:24]1[c:25]([OH:39])[c:26]([Cl:38])[cH:27][c:28]([O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:29]1.[OH:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1.[OH:1][CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1>>[O:1]([CH2:2][CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1)[c:25]1[c:24]([Cl:23])[cH:29][c:28]([O:30][CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:27][c:26]1[Cl:38]

Participants

4

Reactant 3

HCID 996PhenolHCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 120841702,6-Dichloro-4-benzyloxyphenol

Product 1

HCID 58758910Tert-butyl 4-{[2,6-dichloro-4-(phenylmethoxy)phenoxy]methyl}piperidinecarboxylate

Sources & evidence

ORD record
ord-c8a6bcc3423447d2b50c67f5b9dd3d52
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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