Water → 1-(3,4-Methylenedioxyphenyl)-4-morpholino-1-butene-3-ol
Reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][C:12](=[O:20])[CH2:13][N:14]3[CH2:19][CH2:18][O:17][CH2:16][CH2:15]3)=[CH:4][C:3]=2[O:2]1.O>CO>[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[CH:11][CH:12]([OH:20])[CH2:13][N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)=[CH:4][C:3]=2[O:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
27.5 g of the ketone (0.1 M) obtained in Example 1 is dissolved in 300 cm3 of methanol and an aqueous solution of KBH4 is added dropwise. The reaction mixture is left overnight and decomposed with water. The product obtained is filtered and recrystallised in ethanol.
Workup
- additionan aqueous solution of KBH4 is added dropwise
- customThe product obtained
- filtrationis filtered
- customrecrystallised in ethanol
Sources & evidence
- ORD record
- ord-842c2a0ae5a34c11a258e3a737fab6a7
- Source dataset
- uspto-grants-1980_06
- Patent number
- US04209517
Reaction notes
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