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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1707166Generated: October 27, 2026

3-Amino-4-octylthio-2-methylthiomethylbenzotrifluoride → Trifluoromethyl toluidine

https://huagongshe.com/reaction/1707166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-octylthio-2-methylthiomethylbenzotrifluorideHCID 20332853—
Reactant3-Amino-4-bromo-2-methylthiomethylbenzotrifluorideHCID 20332854—
Reactant3-Amino-4-heptylthio-2-methylthiomethylbenzotrifluorideHCID 20332862—
Reactant3-Amino-4-iodo-2-methylthiomethylbenzotrifluorideHCID 20332864—
Reactant3-Amino-4-ethylthio-2-methylthiobenzotrifluorideHCID 20332865—
Reactant3-Amino-4-methyl-2-methylthiomethylbenzotrifluorideHCID 20332871—
Reactant3-Amino-4-chloro-2-methylthiomethylbenzotrifluorideHCID 23352985—
Reactant3-Amino-4-n-propylthio-2-methylthiomethylbenzotrifluorideHCID 53901531—
Reactant3-Amino-4-n-butylthio-2-methylthiomethylbenzotrifluorideHCID 54091637—
ProductTrifluoromethyl toluidineHCID 2735932—

Reaction Steps

Similarly, the 3-amino-4-chloro-2-methylthiomethylbenzotrifluoride may be replaced with equivalent quantities of 3-amino-4-bromo-2-methylthiomethylbenzotrifluoride, 3-amino-4-iodo-2-methylthiomethylbenzotrifluoride, 3-amino-4-methyl-2-methylthiomethylbenzotrifluoride, 3-amino-4-ethylthio-2-methylthiobenzotrifluoride, 3-amino-4-n-propylthio-2-methylthiomethylbenzotrifluoride, 3-amino-4-n-butylthio-2-methylthiomethylbenzotrifluoride, 3-amino-4-heptylthio-2-methylthiomethylbenzotrifluoride, or 3-amino-4-octylthio-2-methylthiomethylbenzotrifluoride, and by following substantially the teachings of Step C of this example, there is produced 3-amino-2-methylbenzotrifluoride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04209464
Source datasetuspto-grants-1980_06
ORD IDord-dc768ed1bb3b4c7aa2875fa676c5cbc6
Source noteuspto-grants-1980_06