N-Benzyl-2-(piperazin-1-yl)ethan-1-amine → HCID 15224927, compound
Reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[C:20]1([CH2:26][NH:27][CH2:28][CH2:29][N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11]([N:33]3[CH2:34][CH2:35][N:30]([CH2:29][CH2:28][NH:27][CH2:26][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:31][CH2:32]3)=[O:12])[C:4]=2[CH:3]=1Participants
3
Procedure
The title compound of Example 2 (0.72 g, 2.45 mmol) was combined with N-(phenylmethyl)-1-piperazineethanamine (0.75 g, 3.40 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic separation, 0.52 g of the white solid title product was obtained.
Workup
- customseparation