Benzenamine, N-methyl-2-nitro-4-(trifluoromethyl)- → N1-Methyl-4-(trifluoromethyl)benzene-1,2-diamine

HRID 1709209Notes

Reaction equation

HRID 1709209 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][C:4]=1[N+:13]([O-])=O>C(O)C.[Pd]>[NH2:13][C:4]1[CH:5]=[C:6]([C:9]([F:10])([F:11])[F:12])[CH:7]=[CH:8][C:3]=1[NH:2][CH3:1]

Participants

4

Reactant 1

HCID 88405Benzenamine, N-methyl-2-nitro-4-(trifluoromethyl)-

Product 1

HCID 715666N1-Methyl-4-(trifluoromethyl)benzene-1,2-diamine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 1.1 g (5.0 mmol) 4-methylamino-3-nitrobenzotrifluoride in 200 ml ethanol was hydrogenated at atm. pressure by using 5% Pd-C (0.15 g) as a catalyst. The reaction mixture was filtered and evaporated in vacuo to give 3-amino-4-methylaminobenzotrifluoride as crystals.

Workup

  1. filtrationThe reaction mixture was filtered
  2. customevaporated in vacuo

Sources & evidence

ORD record
ord-c7dee6f09bf54dd88618ac53961d34f9
Source dataset
uspto-grants-1990_08
Patent number
US04948794

Reaction notes

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