Acetic Anhydride → Butyrate

Reaction equation

C(OC(=O)C)(=O)C.[C:8]([OH:15])(=[O:14])[CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]>>[C:8]([O-:15])(=[O:14])[CH2:9][CH2:10][CH3:11].[C:8]([O-:15])(=[O:14])[CH2:9][CH2:10][CH2:11][CH3:12].[C:8]([O-:15])(=[O:14])[CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 8892Hexanoic Acid

Product 3

HCID 104775Butyrate

HCID 114781Valerate

HCID 4398339Hexanoate

Procedure

A, but substituting for acetic anhydride, the anhydrides or halides of propionic, butanoic, pentanoic, or hexanoic acid, the corresponding manoalide delta-lactone propionate, butanoate, pentanoate, and hexanoate are prepared.

Sources & evidence

ORD record: ord-d4bf6966ef264ee0835f97965a13880a
Source dataset: uspto-grants-1990_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04952605

Reaction notes

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