3-Methoxybenzyl bromide → HCID 12069597, compound
Reaction equation
[OH:1][C:2]1[C:3]([CH3:23])=[C:4]([C:11]([C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=2)=[O:12])[N:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2.[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29]Br>>[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:31]=[CH:32][CH:33]=1)[CH2:29][O:1][C:2]1[C:3]([CH3:23])=[C:4]([C:11]([C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][CH:14]=2)=[O:12])[N:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2Participants
3
Procedure
This compound is obtained according to the same procedure as that of Example 86, by O-alkylation of methyl 4-[(1-hydroxy-2-methylindolizin-3-yl)carbonyl]benzoate with 3-methoxybenzyl bromide. A yellow powder is obtained which melts at 106° C.
Workup
- customThis compound is obtained
- customA yellow powder is obtained which melts at 106° C.
Sources & evidence
- ORD record