ethyl 4-bromo-3-methoxy-1H-indazole-1-carboxylate → 5-Bromo-3-methoxy-indazole-1-carboxylic acid ethyl ester
Reaction equation
C(OC(N1C2C(=CC=C([Br:15])C=2)C(O)=N1)=O)C.[CH2:17]([O:19][C:20]([N:22]1[C:30]2[C:25](=[C:26](Br)[CH:27]=[CH:28][CH:29]=2)[C:24]([O:32][CH3:33])=[N:23]1)=[O:21])[CH3:18]>>[CH2:17]([O:19][C:20]([N:22]1[C:30]2[C:25](=[CH:26][C:27]([Br:15])=[CH:28][CH:29]=2)[C:24]([O:32][CH3:33])=[N:23]1)=[O:21])[CH3:18]Participants
3
Procedure
5-Bromo-3-methoxy-indazole-1-carboxylic acid ethyl ester CCXXXVI was prepared from 6-bromo-3-hydroxy-indazole-1-carboxylic acid ethyl ester using the procedure described for preparation of 4-Bromo-3-methoxy-indazole-1-carboxylic acid ethyl ester CLXXXV (Example 37).
Sources & evidence
- ORD record
- ord-97b173bdcc4d4c43aacd3e67e7c2f34b
- Source dataset
- uspto-grants-2010_09