Imidazole → HCID 13491437, compound

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH3:11].[NH:12]1[CH:16]=[CH:15][N:14]=[CH:13]1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([N:12]1[CH:16]=[CH:15][N:14]=[CH:13]1)=[C:5]2[CH3:11]

Participants

Reactant 2

HCID 795Imidazole

HCID 110192135-chloro-3-methyl-1H-indole

Product 1

HCID 13491437HCID 13491437, compound

Procedure

Condensation of 5-chloro-3-methylindole with imidazole according to the procedure described in the previous examples gives 5-chloro-2-(1-imidazolyl)-3-methylindole, m.p. 212°-215°.

Sources & evidence

ORD record: ord-62130aa08f1b4bceaa11173b8f6ebe11
Source dataset: uspto-grants-1985_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04539410

Reaction notes

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