2,3-Dibromopropene → HCID 22415624, compound

Reaction equation

[C:1]1([C:7]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)=[N:8][CH2:9][P:10]([CH2:15][N:16]=[C:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)(=[O:14])[O:11][CH2:12][CH3:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:36][C:37]([CH2:39]Br)=[CH2:38]>>[C:24]1([C:17]([C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[N:16][CH:15]([P:10]([CH:9]([N:8]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH2:39][C:37]([Br:36])=[CH2:38])(=[O:14])[O:11][CH2:12][CH3:13])[CH2:39][C:37]([Br:36])=[CH2:38])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

Reactant 2

HCID 105522,3-Dibromopropene

HCID 11038164HCID 11038164, compound

Product 1

HCID 22415624HCID 22415624, compoundYield 71%

Procedure

Analogously to Example 6, the bis-alkylated phosphinates 9 were prepared in a yield of 71% from the protected phosphinate 3 and 2,3-dibromopropene.

Sources & evidence

ORD record: ord-d73a845cb2a34394984b323818a9b3b8
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05510504

Reaction notes

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