Thieno[2,3-b]pyridin-3-amine → HCID 67109574, compound

HRID 1725534

Reaction equation

HRID 1725534 reaction equation
[C:1]([C:4]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:8][N:7]([CH2:16][CH3:17])[C:6](=[O:18])[C:5]=1[N+:19]([O-])=O)(=[O:3])[CH3:2].[S:22]1[C:26]2=[N:27][CH:28]=[CH:29][CH:30]=[C:25]2[C:24](N)=[CH:23]1>>[C:1]([C:4]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:8][N:7]([CH2:16][CH3:17])[C:6](=[O:18])[C:5]=1[NH:19][C:24]1[C:25]2[C:26](=[N:27][CH:28]=[CH:29][CH:30]=2)[S:22][CH:23]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 289923Thieno[2,3-b]pyridin-3-amineHCID 107320155-acetyl-2-ethylnitro6-phenylpyridazin-3(2H)-one

Product 1

HCID 67109574HCID 67109574, compound

Procedure

Obtained, (27%) from 5-acetyl-2-ethyl-4-nitro-6-phenylpyridazin-3(2H)-one (Dal Piaz, V et al, J. Med. Chem. 1997, 40, 1417) and thieno[2,3-b]pyridin-3-ylamine (Klemm, L. H., Zell, R., Barnish, I. T., Klemm, R. A., J. Het. Chem, 1970, 373-379) following the procedure of Example 67.

Workup

  1. customObtained

Sources & evidence

ORD record
ord-0e9e267ab9fa4afcb9a99d234bc05e2e
Source dataset
uspto-grants-2009_02
Patent number
US07491722B2

Linked notes

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