Methanol → 1-((1H-indol-4-yl)methyl)-9-(quinoxalin-2-yl)-1,9-diazaspiro[5.5]undecan-2-one

HRID 172600

Reaction equation

HRID 172600 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH3:49][OH:50].[Cs+:5].[Cs+:6].[n:7]1[c:8]([N:17]2[CH2:18][CH2:19][C:20]3([CH2:21][CH2:22][CH2:23][C:24](=[O:46])[N:25]3[CH2:26][c:27]3[c:28]4[cH:29][cH:30][n:31]([S:36]([c:37]5[cH:38][cH:39][c:40]([CH3:41])[cH:42][cH:43]5)(=[O:44])=[O:45])[c:32]4[cH:33][cH:34][cH:35]3)[CH2:47][CH2:48]2)[cH:9][n:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12>>[n:7]1[c:8]([N:17]2[CH2:18][CH2:19][C:20]3([CH2:21][CH2:22][CH2:23][C:24](=[O:46])[N:25]3[CH2:26][c:27]3[c:28]4[cH:29][cH:30][nH:31][c:32]4[cH:33][cH:34][cH:35]3)[CH2:47][CH2:48]2)[cH:9][n:10][c:11]2[cH:12][cH:13][cH:14][cH:15][c:16]12

Participants

5

Reactant 4

HCID 887MethanolHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 672524679-(quinoxalin-2-yl)-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecan-2-one

Product 1

HCID 672523781-((1H-indol-4-yl)methyl)-9-(quinoxalin-2-yl)-1,9-diazaspiro[5.5]undecan-2-one

Sources & evidence

ORD record
ord-f0999c12c322498fb699357d05349b42
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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