1-Benzyl-N-cyclopropylpiperidin-4-amine → Tert-butyl 2-(2-((1-benzylpiperidine-4-yl)(cyclopropyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

HRID 172664

Reaction equation

HRID 172664 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[c:10]([CH3:21])[n:11][c:12]([O:16][CH2:17][C:18](=[O:19])[OH:20])[n:13][c:14]1[CH3:15].[CH2:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[N:29]1[CH2:30][CH2:31][CH:32]([NH:35][CH:36]2[CH2:37][CH2:38]2)[CH2:33][CH2:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[c:10]([CH3:21])[n:11][c:12]([O:16][CH2:17][C:18](=[O:20])[N:35]([CH:32]2[CH2:31][CH2:30][N:29]([CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:34][CH2:33]2)[CH:36]2[CH2:37][CH2:38]2)[n:13][c:14]1[CH3:15]

Participants

3

Reactant 2

HCID 27354811-Benzyl-N-cyclopropylpiperidin-4-amineHCID 593361682-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acid

Product 1

HCID 59336137Tert-butyl 2-(2-((1-benzylpiperidine-4-yl)(cyclopropyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

Sources & evidence

ORD record
ord-914dc7631ca740d987e682f4f7a574a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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