Methanol → Methyl 4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate

HRID 172703

Reaction equation

HRID 172703 reaction equation
[CH3:23][OH:24].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N+:10]([O-:16])=[O:17])[CH:13]([C:14]([O:11][CH3:12])=[O:15])[C:18](=[O:19])[O:20][CH3:21])[cH:6][cH:7]1.[Ni:22]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][NH:10][C:14](=[O:15])[CH:13]2[C:18](=[O:19])[O:20][CH3:21])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 935NickelHCID 5095674Methyl 3-(4-chlorophenyl)-2-methoxycarbonyl-4-nitrobutanoate

Product 1

HCID 3315516Methyl 4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate

Sources & evidence

ORD record
ord-82871d95f56a4e82a62987b53a870f7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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