Acetonitrile → 1-(Bromomethyl)-3-(tetradecyloxy)benzene

HRID 1728810Notes

Reaction equation

HRID 1728810 reaction equation
[CH2:1]([O:15][C:16]1[CH:17]=[C:18]([CH2:22]O)[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C(#N)C.P(Br)(Br)[Br:28]>N1C=CC=CC=1>[Br:28][CH2:22][C:18]1[CH:19]=[CH:20][CH:21]=[C:16]([O:15][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH:17]=1

Participants

5

Reactant 3

HCID 6342AcetonitrileHCID 24614Phosphorus tribromideHCID 100417103-(Tetradecyloxy)benzenemethanol

Product 1

HCID 99772501-(Bromomethyl)-3-(tetradecyloxy)benzene

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The title compound is prepared by the procedure of Example 20 using 2.5 g of product from Example 24, 10 ml acetonitrile, 0.339 g of pyridine and 2.11 g of phosphorus tribromide. The product, 2.27 g, is obtained as colorless needles.

Workup

  1. customThe product, 2.27 g, is obtained as colorless needles

Sources & evidence

ORD record
ord-f7937b16c2344fb6b94fb9dc6ddf0503
Source dataset
uspto-grants-1994_07
Patent number
US05328921

Reaction notes

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