1-Phenylcyclohexane-1-carboxylic acid → Methyl 1-phenylcyclohexane-1-carboxylate

HRID 1729067

Reaction equation

HRID 1729067 reaction equation
[C:1]1([C:7]2([C:13]([OH:15])=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:16]OC(C1CCCC1)=O>CCOCC>[CH3:16][O:14][C:13]([C:7]1([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)=[O:15]

Participants

4

Reactant 2

HCID 708171-Phenylcyclohexane-1-carboxylic acidHCID 78365Methyl cyclopentanecarboxylate

Product 1

HCID 15105202Methyl 1-phenylcyclohexane-1-carboxylate

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

This compound was prepared (1.91 g, 8.76 mmol, 89%) from the product of Step A (2.00 g, 9.8 mmol) following the procedure for synthesis of methyl-1-cyclopentanecarboxylate as set forth in Step A, Example 1. The product of this step was homogeneous by TLC (ether:C2Cl2, 2:1) and used in the next step without further purification. CIMS 219 m/z (M+1).

Workup

  1. customused in the next step without further purification

Sources & evidence

ORD record
ord-a3d1cba68a344dc4abd002d70273a898
Source dataset
uspto-grants-1994_07
Patent number
US05331010

Linked notes

Loading…