Benzamide → 4'-Nitrobenzanilide

HRID 1729114Notes

Reaction equation

[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([O-:12])=[O:11]>>[N+:10]([C:13]1[CH:18]=[CH:17][C:16]([NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:15][CH:14]=1)([O-:12])=[O:11]

Participants

Reactant 2

HCID 2331Benzamide

HCID 7416Nitrobenzene

Product 1

HCID 769304'-Nitrobenzanilide

Procedure

This example illustrates the direct coupling of benzamide and nitrobenzene to give 4'-nitrobenzanilide.

Sources & evidence

ORD record: ord-b58b80e55d334fe6823d55895280ef2d
Source dataset: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05331099

Reaction notes

Loading…