Ethylamine → N-ethyl-3-(4-benzoylphenyloxy)propylamine
Reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:19]=[CH:18][C:9]([C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:11])=[CH:8][CH:7]=1.[CH2:20]([NH2:22])[CH3:21]>C(Cl)(Cl)Cl>[CH2:20]([NH:22][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:19]=[CH:18][C:9]([C:10](=[O:11])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)[CH3:21]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 90 °C
Procedure
1.0 g of 4-(3-bromopropyloxy)benzophenone was dissolved in a 70% aqueous ethylamine solution, and then stirred at 90° C. for 5 hours. The mixture was dissolved in 50 ml of chloroform, washed with water three times, dried over anhydrous sodium sulfate and then concentrated to obtain 0.9 g of N-ethyl-3-(4-benzoylphenyloxy)propylamine.