HCID 21804453, compound → HCID 21804447, compound
Reaction equation
[CH2:1]([C:5]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][CH:13]=2)[C:9](=[O:21])[CH:8]=[CH:7][CH:6]=1)[CH2:2][CH2:3][CH3:4]>CO.[Ni]>[NH2:18][C:15]1[CH:14]=[CH:13][C:12]([CH2:11][N:10]2[C:5]([CH2:1][CH2:2][CH2:3][CH3:4])=[CH:6][CH:7]=[CH:8][C:9]2=[O:21])=[CH:17][CH:16]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A solution of 1.7 g of 6-butyl-1-p-nitrobenzyl-1,2-dihydro-2-oxopyridine in 50 ml of methanol is hydrogenated on 1.7 g of Raney Ni at 20° until the uptake of H2 has ceased. The mixture is filtered and evaporated to give 1-p-aminobenzyl-6-butyl-1,2-dihydro-2-oxopyridine.
Workup
- filtrationThe mixture is filtered
- customevaporated
Sources & evidence
- ORD record
- ord-0334e2bb363b4611b735e8e501b32f86
- Source dataset
- uspto-grants-1994_07
- Patent number
- US05332750
Reaction notes
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