2,4,6-Triaminopyrimidine → HCID 13670795, compound
Reaction equation
[CH:1](=[C:8]([C:14]([CH3:16])=O)[C:9]([O:11][CH2:12][CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[N:23]=[C:22]([NH2:24])[CH:21]=[C:20]([NH2:25])[N:19]=1>C(O)(=O)C>[NH2:17][C:18]1[N:19]=[C:20]([NH2:25])[C:21]2[CH:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:14]([CH3:16])[NH:24][C:22]=2[N:23]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2.2 g (10 mmol) of ethyl 2-benzylideneacetoacetate were heated under reflux for 10 hours together with 1.3 g (10 mmol) of 2,4,6-triaminopyrimidine in 25 ml of glacial acetic acid. The reaction mixture was then cooled to room temperature, and the precipitated product was filtered off with suction and recrystallized as the acetate from acetonitrile.