1-(2-Nitropropoxy)-2,2,5,5-tetramethylcyclopentane → HCID 13878920, compound
Reaction equation
[N+:1]([CH:4]([CH3:16])[CH2:5][O:6][CH:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][CH2:9][C:8]1([CH3:15])[CH3:14])([O-])=O>CO.[Ni]>[NH2:1][CH:4]([CH3:16])[CH2:5][O:6][CH:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][CH2:9][C:8]1([CH3:15])[CH3:14]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
1-(2-Nitropropoxy)-2,2,5,5-tetramethylcyclopentane is dissolved in methanol and hydrogenated at 50 psi with Raney nickel T-1 as a catalyst. The reaction mixture is filtered through Celite and evaporated to yield 1-(2-aminopropoxy)-2,2,5,5-tetramethylcyclopentane.
Workup
- filtrationThe reaction mixture is filtered through Celite
- customevaporated
Sources & evidence
- ORD record
- ord-acf112673a704806bfbc68bbdd0ab630
- Source dataset
- uspto-grants-1986_11
- Patent number
- US04622418
Reaction notes
Loading…