Ammonia → N,N-Dimethylaminopropyl acrylamide

HRID 1732222

Reaction equation

HRID 1732222 reaction equation
O[CH2:2][CH2:3][C:4]([NH2:6])=[O:5].[CH3:7][N:8]([CH3:13])[CH2:9][CH2:10][CH2:11]N.N.[OH-].[Na+]>>[CH3:7][N:8]([CH3:13])[CH2:9][CH2:10][CH2:11][NH:6][C:4](=[O:5])[CH:3]=[CH2:2]

Participants

5

Reactant 4

HCID 222AmmoniaHCID 7993N,N-Dimethyl-1,3-propanediamineHCID 14798Sodium HydroxideHCID 41451403-Hydroxypropanamide

Product 1

HCID 77452N,N-Dimethylaminopropyl acrylamide

Procedure

59.3 g of β-hydroxypropionic acid amide and 68 g of 3-dimethylaminopropylamine were heated for 5 hours in a temperature range of 125°-168° C. until the evolution of ammonia was complete. After adding 1 g of pulverised sodium hydroxide the reaction mixture was distilled.

Workup

  1. distillationwas distilled

Sources & evidence

ORD record
ord-9fb2048b1977420aad17c78493b3ea51
Source dataset
uspto-grants-1980_12
Patent number
US04237067

Linked notes

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