HCID 13151858, compound → HCID 20255497, compound

Reaction equation

[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3[CH:12]=[C:13]([C:16](O)=[O:17])[CH:14]=[CH:15][C:9]=3[CH2:8][CH2:7][C:6]=2[CH:19]=1.C1C2CCC3C=CC=CC=3SC=2C=C(C(O)=O)C=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3[CH:12]=[C:13]([CH2:16][OH:17])[CH:14]=[CH:15][C:9]=3[CH2:8][CH2:7][C:6]=2[CH:19]=1

Participants

Reactant 2

HCID 13151858HCID 13151858, compound

HCID 20306168HCID 20306168, compound

Product 1

HCID 20255497HCID 20255497, compound

Procedure

Repeat the process of Example 1, substituting an equivalent quantity of 8-fluoro-10,11-dihydrodibenzo[b,f]thiepin-3-carboxylic acid for the 10,11-dihydrodibenzo[b,f]thiepin-3-carboxylic acid, to obtain the title product (m.p., 80°-81° C.).

Sources & evidence

ORD record: ord-e462b53c5bdb4976957bd28c01d6435f
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04237160

Reaction notes

Loading…