HCID 13332658, compound → HCID 20255496, compound

Reaction equation

[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3[CH:12]=[C:13]([CH2:16][OH:17])[CH:14]=[CH:15][C:9]=3[CH:8]=[CH:7][C:6]=2[CH:18]=1.[OH:19]CC1C=CC2C=CC3C=CC=CC=3SC=2C=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11](=[O:19])[C:10]3[CH:12]=[C:13]([CH2:16][OH:17])[CH:14]=[CH:15][C:9]=3[CH:8]=[CH:7][C:6]=2[CH:18]=1

Participants

Reactant 2

HCID 13332658HCID 13332658, compound

HCID 20255500HCID 20255500, compound

Product 1

HCID 20255496HCID 20255496, compound

Procedure

Repeat the process of Example 2, substituting an equivalent quantity of 8-fluoro-3-hydroxymethyldibenzo[b,f]thiepin for the 3-hydroxymethyldibenzo[b,f]thiepin to obtain the title product (m.p., 161°-163° C.).

Sources & evidence

ORD record: ord-609b20d1906144ccbd407b1033615b07
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04237160

Reaction notes

Loading…