Imidazo(1,2-a)pyridine-3-carboxylic acid → Tert-butyl 3-[(imidazo[1,2-a]pyridine-3-carbonylamino)methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate

HRID 173449

Reaction equation

HRID 173449 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH2:15].[n:16]1[cH:17][c:18]([C:25](=[O:26])[OH:27])[n:19]2[c:20]1[cH:21][cH:22][cH:23][cH:24]2>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH:15][C:25]([c:18]1[cH:17][n:16][c:20]2[n:19]1[cH:24][cH:23][cH:22][cH:21]2)=[O:26]

Participants

3

Reactant 2

HCID 73142Imidazo(1,2-a)pyridine-3-carboxylic acidHCID 76739429Tert-butyl 3-(aminomethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate

Product 1

HCID 77222974Tert-butyl 3-[(imidazo[1,2-a]pyridine-3-carbonylamino)methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate

Sources & evidence

ORD record
ord-c49e7e62ed5b4b1aada2b6489d809f4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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