4-(Pyrimidin-5-ylamino)benzonitrile → 5-[N-(4-Cyanophenyl)-N-[(2-fluoropyridin-5-yl)methyl]amino]pyrimidine

HRID 1735777Notes

Reaction equation

HRID 1735777 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[CH:11]=[N:12][CH:13]=[N:14][CH:15]=2)=[CH:5][CH:4]=1)#[N:2].Br[CH2:17][C:18]1[CH:19]=[CH:20][C:21]([F:24])=[N:22][CH:23]=1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([C:10]2[CH:15]=[N:14][CH:13]=[N:12][CH:11]=2)[CH2:17][C:18]2[CH:19]=[CH:20][C:21]([F:24])=[N:22][CH:23]=2)=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 105358714-(Pyrimidin-5-ylamino)benzonitrileHCID 220506385-(Bromomethyl)-2-fluoropyridine

Product 1

HCID 153166465-[N-(4-Cyanophenyl)-N-[(2-fluoropyridin-5-yl)methyl]amino]pyrimidine

Procedure

Starting compounds: 5-[N-(4-cyanophenyl) amino]pyrimidine and 5-(bromomethyl)-2-fluoropyridine

Sources & evidence

ORD record
ord-839818427f1b404aa19d4836779b18a4
Source dataset
uspto-grants-1996_07
Patent number
US05538976

Reaction notes

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