2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 5-Cyclopropyl-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)propan-2-yl)-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamide

HRID 173768

Reaction equation

HRID 173768 reaction equation
[CH3:40][C:41]([NH2:42])([c:43]1[n:44][o:45][c:46]([CH3:48])[n:47]1)[CH3:49].[CH:1]1([c:4]2[cH:5][cH:6][c:7]([C:18](=[O:19])[OH:20])[n:8][c:9]2[O:10][CH2:11][CH:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[CH2:2][CH2:3]1.[CH:21]1([c:22]2[cH:23][cH:24][c:25]([C:26]([OH:27])=[O:28])[n:29][c:30]2[O:31][CH2:32][CH:33]2[CH2:34][CH2:35][CH2:36][O:37]2)[CH2:38][CH2:39]1>>[CH:1]1([c:4]2[cH:5][cH:6][c:7]([C:18](=[O:20])[NH:42][C:41]([CH3:40])([c:43]3[n:44][o:45][c:46]([CH3:48])[n:47]3)[CH3:49])[n:8][c:9]2[O:10][CH2:11][CH:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 710872545-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acidHCID 710875605-Cyclopropyl-6-(tetrahydro-pyran-4-ylmethoxy)-pyridine-2-carboxylic acid

Product 1

HCID 710877235-Cyclopropyl-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)propan-2-yl)-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamide

Sources & evidence

ORD record
ord-ab519aa9ef014e80b8f3b702757a955b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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