Dichloromethane → 1-(2-chloro-4-fluoro-5-hydroxyphenyl)-1,4-dihydro-4-ethyl-5H-tetrazol-5-one

Reaction equation

[B:19]([Br:20])([Br:21])[Br:22].[CH2:23]([Cl:24])[Cl:25].[Cl:1][c:2]1[c:3](-[n:11]2[n:12][n:13][n:14]([CH2:17][CH3:18])[c:15]2=[O:16])[cH:4][c:5]([O:9][CH3:10])[c:6]([F:8])[cH:7]1>>[Cl:1][c:2]1[c:3](-[n:11]2[n:12][n:13][n:14]([CH2:17][CH3:18])[c:15]2=[O:16])[cH:4][c:5]([OH:9])[c:6]([F:8])[cH:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 143493591-(2-chloro-4-fluoro-5-methoxyphenyl)-1,4-dihydro-4-ethyl-5H-tetrazol-5-one

Product 1

HCID 198828301-(2-chloro-4-fluoro-5-hydroxyphenyl)-1,4-dihydro-4-ethyl-5H-tetrazol-5-one

Sources & evidence

ORD record: ord-8515b16e6ca948729e9512becea2f4bc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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