(3-Bromopropyl)benzene → 4-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(4-phenylbutyl)pyridine

HRID 1740980

Reaction equation

HRID 1740980 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1.Br[CH2:17][CH2:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:17][CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1

Participants

3

Reactant 2

HCID 12503(3-Bromopropyl)benzeneHCID 224907362-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,6-dimethylpyridine

Product 1

HCID 218344204-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(4-phenylbutyl)pyridine

Procedure

By analogy to Example 53, Step B, the anion of 4,6-dimethyl-2-(2,5-dimethylpyrrol-1-yl)pyridine was alkylated with 1-bromo-3-phenylpropane to give 4-methyl-2-(2,5-dimethylpyrrol-1-yl)-6-(4-phenylbutyl)pyridine.

Sources & evidence

ORD record
ord-9dd4d0b6b9c344848b994decebffd1ac
Source dataset
uspto-grants-1999_10
Patent number
US05972975

Linked notes

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