2-Ethylhexanol → 6-Chloro-4-(2-ethylhexyloxy)-2-i-propylpyrimidine

HRID 1742763

Reaction equation

HRID 1742763 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:13]=CC=C[CH:9]=2)[N:5]=[C:4]([O:14][CH2:15][CH2:16][CH:17]([CH3:19])C)[CH:3]=1.ClC1C=C(Cl)N=[C:23]([C:28]2C=CC=[CH:30][CH:29]=2)N=1.ClC1C=C(Cl)N=C(C(C)C)N=1.C(C(CCCC)CO)C>CC(C)CCO>[Cl:1][C:2]1[N:7]=[C:6]([CH:8]([CH3:9])[CH3:13])[N:5]=[C:4]([O:14][CH2:15][CH:16]([CH2:17][CH3:19])[CH2:23][CH2:28][CH2:29][CH3:30])[CH:3]=1

Participants

6

Reactant 4

HCID 77202-EthylhexanolHCID 77338FenclorimHCID 124409024,6-Dichloro-2-(propan-2-yl)pyrimidineHCID 190067994-Chloro-6-(3-methylbut-1-oxy)-2-phenylpyrimidine

Product 1

HCID 190068006-Chloro-4-(2-ethylhexyloxy)-2-i-propylpyrimidine

Reagents, catalysts & solvents 1

HCID 31260Isoamyl AlcoholSolvent

Procedure

The compound of Example 23 is prepared analogously to the compound of Example 3, with 4,6-dichloro-2-phenylpyrimidine being replaced by 4,6-dichloro-2-i-propylpyrimidine and 3-methylbutanol by 2-ethylhexanol.

Sources & evidence

ORD record
ord-6e52ac7fa15143598625e05c32c4fae4
Source dataset
uspto-grants-1994_08
Patent number
US05340701

Linked notes

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