N-(2-chlorobenzyl)-2,2-dioxo-1,2,3-oxathiazolidine → N-((2-chlorophenyl)methyl)thiophene-3-ethylamine

HRID 1743026Notes

Reaction equation

HRID 1743026 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][N:5]1[CH2:9][CH2:8]OS1(=O)=O.[S:16]1[CH:20]=[CH:19][CH:18]=[C:17]1[Li]>>[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][NH:5][CH2:9][CH2:8][C:17]1[S:16][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 15227704N-(2-chlorobenzyl)-2,2-dioxo-1,2,3-oxathiazolidineHCID 178418439HCID 178418439, compound

Product 1

HCID 6454012N-((2-chlorophenyl)methyl)thiophene-3-ethylamine

Procedure

contacting the N-(2-chlorobenzyl)-2,2-dioxo-1,2,3-oxathiazolidine with thienyllithium to give N-(2-chlorobenzyl)-2-(2-thienyl)ethylamine, and

Sources & evidence

ORD record
ord-7034bc8f83c44f8abaa369a8da91529c
Source dataset
uspto-grants-1994_08
Patent number
US05342953

Reaction notes

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