HCID 66865115, compound → Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

HRID 1745486

Reaction equation

HRID 1745486 reaction equation
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 66865115HCID 66865115, compound

Product 1

HCID 57717476Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared from (2-nitro-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example B2) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (278 mg).

Sources & evidence

ORD record
ord-b522c29a4c5440afa1f96caff081ea3d
Source dataset
uspto-grants-2006_03
Patent number
US07018998B2

Linked notes

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