HCID 71230594, compound → HCID 71230585, compound
Reaction equation
[O:1]=[C:2]1[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:12](=[O:18])[O:13][C:14]([CH3:17])([CH3:16])[CH3:15])[C:5](=[O:19])[NH:4][NH:3]1>C(Cl)Cl>[O:1]=[C:2]1[N:6]([CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:12](=[O:18])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[C:5](=[O:19])[N:4]=[N:3]1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
To tert-butyl 4-(3,5-dioxo-1,2,4-triazolidin-4-yl)butylcarbamate (15 mg, 0.055 mmol) in CH2Cl2 (0.551 mL) was added SiO2—HNO3 (35 mg). The mixture was stirred at room temperature for 15 minutes, then filtered, concentrated in vacuo and dried, giving tert-butyl 4-(3,5-dioxo-3H-1,2,4-triazol-4(5H)-yl)butylcarbamate (I-8c: 15 mg, quantitative yield) as a red oil.
Workup
- filtrationfiltered
- concentrationconcentrated in vacuo
- customdried