Ethyl 3-aminobenzoate → 3-(6-Methyl-pyridine-2-sulfonamido)benzoic acid
Reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:4][CH:3]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=1)[C:16]([O:18]CC)=[O:17].N1C=CC=CC=1S(NC1C=C(C=CC=1)C(O)=O)(=O)=O>>[CH3:1][C:2]1[N:7]=[C:6]([S:8]([NH:12][C:13]2[CH:14]=[C:15]([CH:21]=[CH:22][CH:23]=2)[C:16]([OH:18])=[O:17])(=[O:10])=[O:9])[CH:5]=[CH:4][CH:3]=1Participants
4
Procedure
Intermediate 5b (solid) is prepared using intermediate 4c and ethyl 3-aminobenzoate using the procedure described for 5a.
Sources & evidence
- ORD record
- ord-ff02401bf643433492ff0a7695e72516
- Source dataset
- uspto-grants-2015_10
- Patent number
- US09156834B2
Reaction notes
Loading…