1373822-50-4 → HCID 76684685, compound

Reaction equation

[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]2[N:9]=[C:10]([SH:12])[N:11]=[C:4]2[N:3]=1.[Cl:13][C:14]1[CH:23]=[CH:22][C:17]([O:18][CH2:19][CH2:20]Br)=[CH:16][C:15]=1[F:24]>>[Cl:13][C:14]1[CH:23]=[CH:22][C:17]([O:18][CH2:19][CH2:20][S:12][C:10]2[N:11]=[C:4]3[N:3]=[C:2]([CH3:1])[CH:7]=[C:6]([CH3:8])[N:5]3[N:9]=2)=[CH:16][C:15]=1[F:24]

Participants

Reactant 2

HCID 753609261373822-50-4

HCID 178426287HCID 178426287, compound

Product 1

HCID 76684685HCID 76684685, compoundYield 75%

Procedure

The title compound was prepared according to the experimentals described for Example 1 above from 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-thiol and 4-chloro-3-fluorophenoxy-ethylbromide in 75% yield; EM (calc.): 352.1; MS (ESI) m/e: 353.0 (M+H)+.

Sources & evidence

ORD record: ord-6ce9ff3185394d5a9872eb56756b74be
Source dataset: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09163027B2

Reaction notes

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