2-Pyridinemethanamine → 2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl)nicotinamide

Reaction equation

[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10](-[c:13]3[c:14]([C:15](=[O:16])[NH:17][CH:18]([CH:19]([C:20](=[O:21])[OH:22])[OH:23])[CH2:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[cH:31][cH:32][cH:33][n:34]3)[cH:11][cH:12]2)[cH:6][cH:7]1.[n:35]1[c:36]([CH2:41][NH2:42])[cH:37][cH:38][cH:39][cH:40]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][n:10](-[c:13]3[c:14]([C:15](=[O:16])[NH:17][CH:18]([CH:19]([C:20](=[O:21])[NH:42][CH2:41][c:36]4[n:35][cH:40][cH:39][cH:38][cH:37]4)[OH:23])[CH2:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)[cH:31][cH:32][cH:33][n:34]3)[cH:11][cH:12]2)[cH:6][cH:7]1

Participants

Reactant 2

HCID 195092-Pyridinemethanamine

HCID 672393523-(2-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)nicotinamido)-2-hydroxy-4-phenylbutanoic acid

Product 1

HCID 672378402-(3-(4-Fluorophenyl)-1H-pyrazol-1-yl)-N-(3-hydroxy-4-oxo-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl)nicotinamide

Sources & evidence

ORD record: ord-d1b043d2c5de4ae59a983655db19d954
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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