Benzyl 2,4-dihydroxybenzoate → Benzyl 2-hydroxy-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetoxy)benzoate

HRID 1756441

Reaction equation

HRID 1756441 reaction equation
[OH:1][C:2]1[CH:17]=[C:16]([OH:18])[CH:15]=[CH:14][C:3]=1[C:4]([O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5].[CH3:19][C:20]1([CH3:36])[CH2:29][CH2:28][C:27]([CH3:31])([CH3:30])[C:26]2[CH:25]=[C:24]([CH2:32][C:33](Cl)=[O:34])[CH:23]=[CH:22][C:21]1=2>>[OH:1][C:2]1[CH:17]=[C:16]([O:18][C:33](=[O:34])[CH2:32][C:24]2[CH:23]=[CH:22][C:21]3[C:20]([CH3:19])([CH3:36])[CH2:29][CH2:28][C:27]([CH3:31])([CH3:30])[C:26]=3[CH:25]=2)[CH:15]=[CH:14][C:3]=1[C:4]([O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:5]

Participants

3

Reactant 2

HCID 7500968Benzyl 2,4-dihydroxybenzoateHCID 214744835,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetyl chloride

Product 1

HCID 54418977Benzyl 2-hydroxy-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetoxy)benzoate

Procedure

In a manner similar to Example 1(d), by reaction of 2.44 g (10 mmol) of benzyl 2,4-dihydroxybenzoate with 2.6 g (10 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl -2-naphthylacetyl chloride, 3.9 g (83% ) of the expected ester are obtained in the form of a colorless oil.

Workup

  1. customare obtained in the form of a colorless oil

Sources & evidence

ORD record
ord-610f4cdd293649f0820ca4b4de046fb4
Source dataset
uspto-grants-1995_08
Patent number
US05439925

Linked notes

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