2-Thiopheneboronic acid → HCID 19390971, compound

Reaction equation

[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9](I)[CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1.[S:18]1[CH:22]=[CH:21][CH:20]=[C:19]1B(O)O>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:19]3[S:18][CH:22]=[CH:21][CH:20]=3)[CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1

Participants

Reactant 2

HCID 27339602-Thiopheneboronic acid

HCID 19390960Amino-1-(3-iodophenyl)-benzimidazole

Product 1

HCID 19390971HCID 19390971, compound

Procedure

2-Amino-1-[3-(2-thienyl)phenyl]benzimidazole was prepared from 1-(2-amino-1-benzimidazolyl)-3-iodobenzene and 2-thienylboronic acid by method B. mp 142°-144° C.

Sources & evidence

ORD record: ord-58267b910e9b412c99f7f139b3952ec0
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05441969

Reaction notes

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