Bromomethyl 4-methoxyphenyl ketone → HCID 15388729, compound
Reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH2:9][C:10](=[O:13])[NH:11][N:12]=2)=[CH:3][CH:2]=1.[CH3:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]([CH2:24][Br:25])=[O:23])=[CH:18][CH:17]=1>C(O)C>[Br-:25].[CH3:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]([CH2:24][N+:1]2[CH:2]=[CH:3][C:4]([C:7]3[S:8][CH2:9][C:10](=[O:13])[NH:11][N:12]=3)=[CH:5][CH:6]=2)=[O:23])=[CH:18][CH:17]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2-(4-Pyridyl)-4H,6H-1,3,4-thiadiazin-5-one (1.88 g, 9.74 mmol) and 4'-methoxyphenacyl bromide (2.23 g, 9.74 mmol) were dissolved in absolute ethanol (40 ml) and stirred at room temperature for one day. The resultingprecipitate was collected by filtration and washed with absolute ethanol toobtain the titled compound (3.84g) as yellow powder.