3-(Dimethylamino)-1-(furan-3-yl)prop-2-en-1-one → 4-(3-Furyl)imidazo[1,5-a]pyrimidine-8-carboxamide

HRID 1758796

Reaction equation

HRID 1758796 reaction equation
CN(C)C=CC(C1C=COC=1)=[O:6].[O:13]1[CH:17]=[CH:16][C:15]([C:18]2[N:23]3[CH:24]=[N:25][C:26]([C:27]#[N:28])=[C:22]3[N:21]=[CH:20][CH:19]=2)=[CH:14]1>>[O:13]1[CH:17]=[CH:16][C:15]([C:18]2[N:23]3[CH:24]=[N:25][C:26]([C:27]([NH2:28])=[O:6])=[C:22]3[N:21]=[CH:20][CH:19]=2)=[CH:14]1

Participants

3

Reactant 2

HCID 14746553-(Dimethylamino)-1-(furan-3-yl)prop-2-en-1-oneHCID 20508954HCID 20508954, compound

Product 1

HCID 205089514-(3-Furyl)imidazo[1,5-a]pyrimidine-8-carboxamide

Procedure

3-Dimethylamino-1-(3-furyl)-2-propen-1-one (prepared as described in Example 4) can be substituted for 3-dimethylamino-1-(2-thienyl)-2-propen-1-one (prepared as described in Example 4) in the procedure of Example 6, to produce 4-(3-furyl)imidazo[1,5-a]pyrimidine-8-carboxamide.

Sources & evidence

ORD record
ord-508b68eacaf842549d0a7001ccd6b588
Source dataset
uspto-grants-1983_02
Patent number
US04374988

Linked notes

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