1-[4-(3-Carbomethoxyprop-2-eneoxy)phenyl]propan-2-one → 1-(4-[3-Carbomethoxypropoxy]phenyl)propan-2-one

HRID 1758988Notes

Reaction equation

HRID 1758988 reaction equation
[C:1]([CH:5]=[CH:6][CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16](=[O:18])[CH3:17])=[CH:11][CH:10]=1)([O:3][CH3:4])=[O:2].[H][H]>C(O)C.[Pd]>[C:1]([CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][C:16](=[O:18])[CH3:17])=[CH:13][CH:14]=1)([O:3][CH3:4])=[O:2]

Participants

5

Reactant 2

HCID 538253751-[4-(3-Carbomethoxyprop-2-eneoxy)phenyl]propan-2-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 130796131-(4-[3-Carbomethoxypropoxy]phenyl)propan-2-oneYield 99.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of 1-[4-(3-carbomethoxyprop-2-eneoxy)phenyl]propan-2-one (1.1 g) in ethanol (50 ml), was added 10% Pd/C (100 mg) and the mixture hydrogenated at ambient temperature and atmospheric pressure until hydrogen uptake was complete (approx. 10 minutes). The solution was filtered, evaporated to give the title compound (1.1 g) as an oil.

Workup

  1. customhydrogenated at ambient temperature
  2. custom(approx. 10 minutes)
  3. filtrationThe solution was filtered
  4. customevaporated

Sources & evidence

ORD record
ord-5fe1d94af7b0417cb1bc3a573dc4aeb7
Source dataset
uspto-grants-1982_07
Patent number
US04338333

Reaction notes

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